Beta cells in the pancreas sense glucose levels, they sense the glucose levels changing and they secrete the right amount of insulin at the right time. 胰腺的beta细胞感应葡萄糖浓度的变化,然后及时分泌适当的胰岛素进行调节。
Furthermore, these cells had transformed themselves into the insulin-producing islet beta cells. 并且,母血细胞还自形转化为可以生产胰岛素的胰岛β细胞。
The new device's system is modelled on the cells in the pancreas that produce insulin, called beta cells. 新的设备系统仿照的是胰腺中产生胰岛素的β-细胞。
They converted some of the exocrine cells into beta cells by introducing just three transcription factors molecules that switch genes on and off as cells develop. 通过注入三种转录因子(随着细胞发育,转换基因表达与否的分子),研究人员将一些外分泌细胞转化成β细胞。
Kieffer and colleagues found that weakening leptin signaling to beta cells caused them to malfunction, leading to obesity and disrupted blood sugar levels, even in the absence of overeating. Kieffer及其同事发现,即使不过多饮食,减弱到达β细胞的瘦素信号可使β细胞功能障碍,导致肥胖并影响血糖水平。
Directional differentiation of stem cells into islet beta cells: The transplantation for treating diabetes 干细胞移植定向分化为胰岛β细胞治疗糖尿病
The disease occurs when the immune system attacks insulin producing beta cells in the pancreas, usually destroying them beyond repair before the illness is diagnosed. 该疾病是由于免疫系统攻击胰腺中产生胰岛素的β细胞且在确诊前已完全损毁β细胞。
They made insulin-producing "beta cells" in living mice, by injecting a combination of three genes into other cells in the pancreas. 他们通过将三种基因组合注入胰腺内的其它细胞,在活鼠体内生成分泌胰岛素的“β细胞”。
To date, much of the research has been confined to in vitro rather than in vivo studies of individual beta cells and the Islets of Langerhan. 迄今为止,许多研究还限制在体外,而不是在个体β细胞和郎格汉斯岛的体内试验。
The cells seem to flip directly [ from exocrine to beta cells] within three days, without going through an intermediate stage, said Prof Melton. 梅尔顿教授表示:这些细胞看起来在3天内就完成(从外分泌细胞到β细胞的)直接转换,不需要经过一个中间阶段。
Effect of Rosiglitazone Sodium on the Apoptosis of Beta Cells in Rats with Experimental Type 1 Diabetic Mellitus 罗格列酮钠对实验性1型糖尿病大鼠胰岛β细胞凋亡的影响
The islets contain alpha cells secreting glucagon, beta cells secreting insulin, and delta cells secreting somatostatin. 胰岛包含分泌胰高血糖素的α(A)细胞,分泌胰岛素的β(B)细胞和分泌生长抑素的δ(D)细胞。
He Use of Insulin Secretagogues and their Effects on the Pancreatic Beta Cells 'Function 胰岛素促泌剂及其对胰岛β细胞功能的影响
Study of mechanism of vitamin E preventing pancreatic beta cells from impairment 维生素E抗胰岛β细胞损伤的相关机制研究
Insulin secretion from the beta cells in the part of the pancreas called the Islets of Langerhan is a complicated process, which if it fails to work properly induces diabetes. 在胰腺中叫做郎格汉斯岛的部分的β细胞的胰岛素分泌是一个复杂的过程,当它不能正常工作时诱导糖尿病。
The disposition index, a measure of the relation between the sensitivity of beta cells to glucose and tissue sensitivity to insulin," improved dramatically," according to the investigators. 处置指数,一种测量β细胞对糖敏感性以及组织胰岛素敏感性的方法,研究结果显示其显著改善。
Effects of the second phase injury of hepatic ischemia-reperfusion on the secretion of pancreatic beta cells 肝脏缺血-再灌注2相损伤对胰岛β细胞分泌功能的影响
Insulin is secreted by beta cells, specialized cells in the pancreas. 胰岛素是由胰腺中的特种细胞β细胞分泌的。
Like real beta cells, the chip does not respond to low levels of glucose but is very excitable above a certain threshold. 就像真正的β细胞,芯片对低水平葡萄糖没有反映,而超过一定阈值则很兴奋。
Congenital HI is caused by mutations that damage the insulin-secreting beta cells in the pancreas, which in an infant is smaller than an adult's little finger. 先天性高胰岛素症是由突变所致,在婴儿比成人小手指还小的胰腺中胰岛素分泌β细胞发生了变异。
We can also confirm that diabetic mice which had pancreatic beta cells transplanted onto the eye were completely cured. 我们同样证实胰岛B细胞移植入眼睛的糖尿病鼠是完全治愈的。
The hormone leptin is produced by fat and helps regulate insulin secreted by pancreatic beta cells. 瘦素由脂肪产生,通过胰岛的β细胞协助调节胰岛素的分泌。
Accumulation of lipid and the proliferation of pancreatic islet beta cells 细胞内脂肪堆积和β细胞增殖的关系
Conclusion Short-term Insulin's intensified therapy could improve the function of beta cells of islet and relieve insulin resistance. 结论短期胰岛素强化治疗能改善胰岛β细胞功能,减轻胰岛素抵抗。
This paper discussed the possibilities of the differentiation from stem cells to pancreatic beta cells. 本文讨论干细胞向胰腺beta细胞分化的各种可能性。
Not only the characters and advantages of MSCs, but also the technological approaches and development trend of the committed differentiation into pancreatic beta cells were reviewed. 就间充质干细胞的生物学性状和优势,以及诱导分化为胰岛β细胞的技术方法和发展趋势进行了综述。
Some antigen specific CD8+ T lymphocytes can recognize the self-antigen in the surface of islet beta cells which presented by MHC class I, then they will kill islet beta cells by cytotoxic effect. 抗原特异性CD8+T淋巴细胞可以识别胰岛β细胞表面由MHC-Ⅰ类分子递呈的自身抗原肽,通过分泌穿孔素和颗粒酶等机制发挥细胞毒作用,从而破坏胰岛β细胞。
Thus, islet cell mass in the adult pancreas was maintained by the expansion of progenitor cells and their immediate progenies rather than by the replication of fully differentiated beta cells. 因此,我们的实验结果提示,成年胰腺中胰岛细胞质量的维持主要是通过胰岛祖细胞或其直接后代的增殖,而不是由于已分化的beta细胞的复制来实现的。
Scholars are hoping to search and induced pancreatic stem cells to generate new beta cells through the studies of pancreas development and stem cells. 学者们一直希望通过研究胰腺发育和胰腺干/祖细胞来获得可以被诱导产生新p细胞的胰腺干/祖细胞。
The removed ability of beta cells of islet to ROS is low, causing impair by ROS, cell death or apoptosis which lead to the defective secretion of insulin. 而胰岛β细胞本身对ROS的清除能力较低,容易受到ROS的损伤,引起细胞坏死或凋亡,导致胰岛素的分泌缺失。